详细信息:Millipore's MILLIPLEX MAP EpiQuant EGFR Pathway Magnetic Bead Panel allows for the analysis and absolute quantitation of tyrosine phosphorylation sites on ErbB2 and ErbB3, and multiple sites on ErbB1, as well as tyrosine phosphorylation sites for 16 other receptor related proteins, including ERK1/2 and multiple Gab2 and FAK sites. In addition to containing 20 phosphorylated targets, the assay is also able to quantify total EGFR and a loading control (TAFII68) simultaneously in a single assay well.
The complexity and number of protein targets involved in signaling events, as well as cellular responses, require tools that enable multiplex analysis of samples. Millipore’s MILLIPLEX MAP EpiQuant technology allows for the analysis of a greater number of intracellular analytes per well, as compared to even traditional Luminex intracellular assays. The magnetic bead format of these assays provides additional convenience, with walk-away washing options, and increased consistency, dramatically improve productivity.
