应用:CHEMICON™™'s Cell Transformation Detection Assay (Catalog number ECM570) is a valuable tool for the morphological and quantitative detection of in vitro malignant transformation of cells induced by certain test compounds. This assay also allows screening of substances that inhibit malignant cell transformation.
详细信息:CHEMICON™'s Cell Transformation Detection Assay is an anchorage-independent growth assay in soft agar, which is considered the most stringent assay for detecting malignant transformation of cells. For this assay, cells (pre-treated with carcinogens or carcinogen inhibitors) are cultured with appropriate controls in soft agar medium for 21-28 days. Following this incubation period, formed colonies can either be analyzed morphologically using our cell stain solution or quantified with the cell quantification solution.