详细信息:MMP-16, human, catalytic domain, E. coli recombinant.CC1045 is a recombinant 189 amino acid polypeptide sequence corresponding to Leu91 - Arg279 of mature human MT3-MMP. Produced by activation of a recombinant soluble proform of MT3-MMP purified from E. coli periplasm. The calculared Mr of recombinant catalytic domain is 21095 Da.
INHIBITORS:
The catalytic domain of MT3-MMP is inhibited by tissue inhibitors of matrix metalloproteinases-2 (TIMP-2) and by chelators of divalent cations such as EDTA or o-phenanthroline.